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In human lung cancer cells, NRF2 regulates serine biosynthesis via activating transcription factor 4 (ATF4) and phosphoglycerate dehydrogenase (PHGDH) to support GSH and nucleotide production and coordinately activates the pentose phosphate pathway (PPP) to supply ribose for nucleic acid biosynthesis (29, 107)

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Although the rationale for developing psoriasis is still unknown, some causes are evident, like an overactive immune system, genetic mutations, or environmental triggers

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Finally, NSCs are a specialized type of stem cell which can self-renew and differentiate into various neuronal and glial cells, playing a crucial role in brain development and repair