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Echinocystic acid alleviated hypoxic-ischemic brain damage in neonatal mice by activating the PI3K/Akt/Nrf2 signaling pathway

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doi: 10.1021/acsabm.9b00236, Summary Keywords AMD, drusen, inflammation, melatonin, mitochondrial dysfunction, oxidative stress, photoreceptors Citation Reiter RJ, Sharma R, Blasiak J, Rosales-Corral S and Loh D (2026) Retinal pigment epithelium pathology in age-related macular degeneration: mitigation with melatonin

Transgenic mice represent a powerful tool for physiologists to study genetic, molecular, biochemical, and physiological events in the whole animal, organ, tissue, or cell in vivo, as well as in real time, with resolution and specificity similar to that obtained in cell cultures
