is glutathione in vitreous humor How Can Help the Eyes and Brain? Glutathione and Eye Disease -

Interaction with inflammatory mediators Alterations in pro- and anti-inflammatory cytokines, including interleukin (IL)-6, IL-1 and tumour necrosis factor (TNF), have been reported in populations with depression, and to a lesser extent, bipolar disorder and schizophrenia.16,17 These inflammatory cytokines are potential contributors to the underlying pathophysiology of these disorders

Lee HY, Lee GH, Kim DS, et al

GR stands for glutathione reductase and it's an enzyme that converts oxidized glutathione into a more active, bioavailable version of glutathione, known as 'reduced glutathione'

Most brightening actives target the enzyme tyrosinase, which controls melanin formation

Do not exceed the recommended intake

They also had a 46.2% lower glutathione level than the controls