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Inflammatory cell trafficking across the bloodbrain barrier: chemokine regulation and in vitro models

What makes DSIP particularly interesting is that it appears to cross the blood-brain barrier, which is not something every peptide can do

Here, we observed that bTNF- increases glucose, which leads us to hypothesize that bTNF- modifies cellular metabolism toward a glycolytic state to induce proinflammatory effects

Brand, 1984)
