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The dependence of tyrosine hydroxylase on BH 4 necessitates the coupling to the action of dihydropteridine reductase (encoded by the QDPR gene: quinoid dihydropteridine reductase) as is the situation for tryptophan hydroxylase (see below) and phenylalanine hydroxylase

doi: 10.2147/JIR.S64888 93 WilliamsD

Corpas et al

This method provides a slower, more sustained release of the vitamin into the bloodstream

Then, a 5 mM paraquat solution was added to the NGM plates, and after 4 h of treatment, the worms were collected in PBS buffer and washed 3 times

These findings confirmed that GpoA, AhpD and TpxD play a relevant protective role during oxidative stress, potentially enabling the bacterium to persist in hostile environments encountered in different tissues during infection