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ALS is mostly diagnosed based on clinical signs, using the revised El Escorial criteria, which require signs of both upper motor neuron (e.g., spasticity, brisk reflexes) and lower motor neuron damage (e.g., muscle wasting, twitching) in multiple body regions (Kwan and Vullaganti, 2022)

36,000 mcg, 15 mL Tube: Foals: Administer 2.5 mL orally as needed, or as directed by a veterinarian

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When this process is disrupted, a structural problem called a neural tube defect can occur

Dehydrogenative Pd and Ni catalysis for total synthesis