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While freezing did not impact the concentrations of NAD + , NADH, GSH, or GSSG, it triggered the conversion of NADPH to NADP + , with about 508% of NADP + originating from NADPH oxidation (Supplementary Figure 1m-r)

Glutathione is directly linked to skin-brightening and anti-aging effects

doi: 10.2174/092986708783497337

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