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Nolin TD, Ouseph R, Himmelfarb J, McMenamin ME, Ward RA

A small pool of cytoplasmic free Fe 2+ could directly catalyze the formation of free radical formation via the Fenton Reaction where changes of ferritin expression levels affect the homeostasis of iron metabolism by altering the intracellular free and redox active iron pool

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Knockout of ERN1 was verified by Western blotting and Sanger sequencing

hPSC-derived astrocytes at the forefront of translational applications in neurological disorders