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For D-SIBs, the bank-specific indicators are grouped into four categories: Size how big is its share of domestic banking activity Substitutability how easily can it be replaced as a market participant and financial service provider Complexity how many different services does it offer Interconnectedness how connected is it to other financial institutions For G-SIBs, a fifth category is added: Cross-jurisdictional activity how much activity does it undertake in other financial jurisdictions Canadas systemically important banks Canada has 6 D-SIBs: Bank of Montreal Bank of Nova Scotia Canadian Imperial Bank of Commerce National Bank of Canada Royal Bank of Canada Toronto-Dominion Bank The Royal Bank of Canada and Toronto-Dominion Bank are also considered G-SIBs

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STEVENS-JOHNSON SYNDROME/TOXIC EPIDERMAL NECROLYSIS SJS and TEN are overlapping conditions characterized by mucocutaneous reactions with epidermal necrosis and detachment