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Gurtner, G

Each freeze-thaw cycle creates ice crystals that can physically disrupt peptide structure, and the process concentrates the peptide at the boundary between frozen and unfrozen regions, potentially causing aggregation

A., Bakopoulou, A

Role of short chain fatty acids to counteract inflammatory stress and mucus production in human intestinal HT29-MTX-E12 cells

The compound's mechanism as an NNMT (nicotinamide N-methyltransferase) inhibitor means it competes with dietary nicotinamide for the same metabolic pathway

Proper storage slows these processes and maintains potency throughout the usable life of the vial