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The IPA software also predicted LIF to be an activated upstream regulator

It contains Glutathione, a compound formed by the combination of three amino acids: Cystein, Glutamate, and Glycine

For instance, Zhang and coworkers synthesized a small molecule prodrug that includes an NQO1-responsive trigger group (Q3PA, quinone propionic acid), a self-immolative linkage, and the active drug 5-FU (Figure 5A) (Zhang et al., 2018)

Glycine, produced from L-serine in reaction catalyzed by glycine hydroxymethyltransferase, is degraded by a group of enzymes called the glycine cleavage system to yield carbon dioxide, ammonia, and 5,10-MTHF

10.5935/1518-0557.20240073 [DOI] [PMC free article] [PubMed] [Google Scholar] Chowdhury M

Keep the vial refrigerated after the water is added