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Acknowledgements This work was supported by the National Natural Science Foundation of China (41301568), the Special Fund for Agro-Scientific Research in the Public Interest (201303031), the Science and Technology Plan Projects of Hunan Province (2014NK3078), and the Hunan Agricultural University Introduced Talents Science Foundation (13YJ03)

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Antioxidant-rich foods include fruits, vegetables, nuts, seeds, and whole grains

Rare mutations in TCN2 cause transcobalamin deficiency, which has symptoms of neurological problems, failure to thrive, vomiting, and low blood cell counts

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The trial was carried out in 10 fasting volunteers administered 1 g doses of liposomal and nonliposomal ascorbic acid (Table 1)
