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Furthermore, the skin surface is covered by a lipid mantle and exfoliated epidermis

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Pasteur et al., 2010

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This metabolic imbalance contributes to increased lipid peroxidation, as indicated by high malondialdehyde (MDA) levels ( These mitochondrial impairments not only compromise energy production but also act as pro-inflammatory stimuli, promoting chronic neuroinflammation through dysregulated mitochondrial signaling and innate immune response

Descriptive epidemiology of Parkinson's disease: Distribution and hypothesis formulation
