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As a result, GCI overexpressing SER3 , SHM2 , and CYS4 showed the highest volumetric glutathione production (64.0 4.9 mg/L) at 48 h cultivation, and this value is about 2.5-fold higher than that of the control strain
Cummings DE
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This can occur through the direct interaction of the drug/metabolite with receptors from immune cells or by covalent attachment of the drug to endogenous proteins, in a process known as haptenation

J Neurochem 85:729739
Fenton-reaction-acceleratable magnetic nanoparticles for ferroptosis therapy of orthotopic brain tumors
