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[10] Although the cause of ASC is varied, an association between ASC and the formation of synechiae after trauma or inflammation has been hypothesized

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The PIP5K family member, PIP5K, interacts with the tumor suppressor pRB which results in activation of the enzyme leading to increased production of PIP 2

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This de- and redifferentiation process of BMAds into osteolineage cells has also been detected after injury without irradiation, suggesting the high plasticity of BMAds even in the steady state (214)