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And thats what our professors taught us back in the early 70s in medical school
The method is based on the assumption that the presence of damage in the DNA structure, such as double- and single-strand breaks, modified bases, or their adducts, will hinder the activity of DNA polymerase and decrease the efficiency of the reaction [7]
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Behavioral and Neural Biology, 54(2), 110114
and Boshra, V
