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Mice received a 5-min block of no stimulation (off) followed by the delivery of the optostimulation pattern (on) for 30 minutes (see Optogenetic stimulation protocol section)

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The pattern is dose-dependent in community reports

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These researchers were not the first to suggest that an inadequacy of nutrients was the cause of pernicious anemia, but their particular input was a carefully designed intervention in well-characterized pernicious anemia patients, of a special diet containing large amounts of liver