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however, it is undeniable that reduced glutathione (GSH) is more active and effective than oxidized glutathione Peptide (GSSSG) is even better

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For example, a recent chromatin immunoprecipitation (ChIP)-seq and ChIP-qPCR analysis demonstrated NRF2 binds to the upstream regions of pro-inflammatory cytokine genes, IL-6 and IL-1b and has a suppressive effect on pro-inflammatory (M1) activated macrophages [41]

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Materials and methods: The mPEGPLGA copolymers were synthesized by typical ring-opening polymerization of lactide, glycolide and mPEG as macroinitiators

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