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Mechanisms that regulate stem cell aging and life span

Abstract Drugs can be metabolically activated to soft and hard electrophiles, which are readily trapped by glutathione (GSH) and cyanide (CN), respectively

It helps make the myelin sheath around nerves

A key role for actin-cytoskeletal disarrangement on these functional alterations has been proposed, since it has been causally linked to internalization of canalicular transporters and disarrangement of tight-junctional structures