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Fe-1 affects TGF-1-induced EMT conversion and reverses erastin-induced ferroptosis ( in vivo and in vitro

Experimental studies have shown that Ge Gen Qin Lian Tang can upregulate Nrf2 and HO-1 proteins, inhibit ferroptosis, significantly reduce serum levels of MPO, LPO, and MDA, improve colonic tissue pathological damage and structural integrity in UC rats, thereby treating UC ( The Si Shen Wan composed of Buguzhi ( Cullen corylifolium (L.) Medik.), Wuzhuyu ( Tetradium ruticarpum (A.Juss.) T.G.Hartley), Roudoukou ( Myristica fragrans Houtt.), and Wuweizi ( Schisandra chinensis (Turcz.) Baill.), is known for its kidney-warming, cold-dispelling, and intestine-binding properties

Ultimately, the responses to enzyme induction will need to be interpreted with respect to potential consequences for human health (Francke-Carroll et al

Garrett, Nutr

Retrieved September 27, 2024

A recent scRNA-seq study suggests that paclitaxel-induced transcriptional changes are different from the gene expression pattern of injury-induced neuropathic pain, despite the involvement of macrophages infiltration in the development of CIPN in both peripheral nerve injury models (Renthal et al., 2020)
