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Silibinin effectively remodels the tumor microenvironment by enhancing the activation of NK cells, which boosts their ability to recognize and eradicate breast cancer (4T1, MCF-7, and MDA-MB-231) cells [890]

J Pharm Exp Ther

2016 doi: 10.2174/1381612822666160822150243

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Table 4 lists completed human studies of nano- or bio-engineered phytochemical formulations that were identified in the search and reported in this manuscript

Pharmacological inhibition or genetic deletion of NLRP3 reduces infarct size, attenuates inflammatory cytokine release, and preserves cardiac function in preclinical models