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At the start of the experiment, thirty five (35) apparently healthy adult male Mice between the ages of 8-12 weeks were obtained from the Department of Human Physiology, College of Basic Medical Sciences, Ahmadu Bello University, Zaria, Nigeria animal breeding section

67 RaiA.TripathiP.DwivediS.DubeyS.ShriM.KumarS.et al (2011)

To view a copy of this licence, visit About this article Cite this article Low, C.Y., Gan, W.L., Lai, S.J

In the 15/7.5 mg IBU group, lung WW/DW ratios were significantly lower than in saline-treated mice at 12 h

For dry powder inhalation, mucolytics such as mannitol and sorbitol are recommended to improve particle penetration through mucus by osmotically drawing water into the airway surface, thereby hydrating and loosening the mucus gel layer 195

doi: 10.1038/nature08192 11 StefanssonHOphoffRASteinbergSAndreassenOACichonSRujescuDet al