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With six votes for and six votes against recommending that state and local governments require a prescription, committee Chair Martin Kulldorff cast the vote that sank the proposal

The practical takeaway: AOD-9604 has a clean safety profile in trials but a failed Phase 2b efficacy endpoint

Non-Stimulant Fat Loss Promotes fat reduction without CNS stimulation, making it suitable for evening use and for individuals sensitive to stimulants

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doi: 10.3389/fnut.2025.1701661 Received 08 September 2025 Revised 10 November 2025 Accepted 04 December 2025 Published 05 January 2026 Volume 12 - 2025 Edited by Emanuele Micaglio, IRCCS San Donato Polyclinic, Italy Reviewed by Runzhe Xu, University of Texas Southwestern Medical Center, United States Husain Alkhaldy, King Khalid University, Saudi Arabia Updates Copyright 2026 de Carvalho, Akamine, Di Pietro, Frana, Oliveira and Lopes