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Description
Silencing of glutamate-cysteine ligase (GCLC), a rate-limiting enzyme in GSH biosynthesis, caused an increase in oxidative stress/protein oxidation and downregulation of the the CYP2R1 , CYP27A1 , CYP27B1 , VDBP , and VDR genes in cultured hepatocytes

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Neuro Endocrinol

While the compound has been shown experimentally to help different types of wounds heal, here Ill focus on its musculoskeletal applications (1)

Pt drugs have been reported to result in mitochondrial damage and oxidative stress once they accumulate at DRG (Podratz et al., 2017)
