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Silencing of glutamate-cysteine ligase (GCLC), a rate-limiting enzyme in GSH biosynthesis, caused an increase in oxidative stress/protein oxidation and downregulation of the the CYP2R1 , CYP27A1 , CYP27B1 , VDBP , and VDR genes in cultured hepatocytes

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C.SalavagionneO

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10c, d)

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Neuro Endocrinol

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While the compound has been shown experimentally to help different types of wounds heal, here Ill focus on its musculoskeletal applications (1)

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Pt drugs have been reported to result in mitochondrial damage and oxidative stress once they accumulate at DRG (Podratz et al., 2017)

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