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This late-phase response explains why allergy symptoms often persist long after allergen exposure ends and why chronic allergic conditions like eczema and asthma involve ongoing tissue damage

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Traditional diagnostic approaches often depend on clinicians' subjective judgment, which may lead to misdiagnosis or missed cases

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The following section will review and integrate the available data and suggest further testable hypotheses concerning DBH inhibition and the blockade of norepinephrine synthesis as primary mechanisms underlying disulfiram-induced cocaine abstinence