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Medical hypothesis, discovery & innovation ophthalmology journal, 4(3), 120126

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It helps prevent brain atrophy (loss of neurons in the brain) which eventually prevents dementia and memory loss

When NNMT becomes overactive, particularly in adipose tissue, it depletes cellular NAD+ reserves while promoting fat storage and metabolic inefficiency

2000;53(6):274278) Authors : F

5-amino-1MQ showed concentration-dependent inhibition of NNMT in fully differentiated adipocytes that could be fit to a 3-parameter sigmoidal dose-response curve with a calculated EC 50 = 2.3 +/ 1.1 M (Figures 2E, 2F
