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The triple-agonist mechanism explains why

doi: 10.1038/nri3897 109 NiemiecM

It is also produced by tissues outside the liver where it acts locally in a paracrine fashion and is believed to play an important autocrine role in cancer [4]
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According to Nyembwe et al

This cycle is why glutathione is so central to the conversation about long-term liver wellness

doi: 10.1016/S1081-1206(10)60188-3
