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OXPHOS, oxidative phosphorylation

While the exact cause of AD onset is still unclear, the prevailing hypothesis is that the increase in amyloid- (A) plaques and neurofibrillary tangles (NFTs) in the brain leads to synaptic dysfunction, and thus the onset of AD (Dias et al., 2014

doi: 10.1002/nbm.3275, 112 VaughanJ

Pyroptosis is generally considered as a form of immunogenic cell death (ICD)

Mutations in genes like BRCA2 are well-established in promoting DNA damage and facilitating tumorigenesis in cancers such as breast cancer
