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Blood-brain barrier disruption is increasingly recognized as a key mechanism underlying CSVD progression

Severe allergic reactions to B12 shots are uncommon but can happen

All conversions assume a U-100 insulin syringe, where 1mL equals 100 units and each unit is 0.01mL

[0451] A number of different cleavable linkers are known to those of skill in the art

Notably, the AMSN/DOX group exhibited significantly lower cytotoxicity than the free DOX group in normal liver cells
