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Intriguingly, application of the reducing agent dithiothreitol (DTT) blocked copper mediated inhibition of kainate-induced currents, suggesting an oxidative mechanism, rather than direct binding, may be partly responsible for coppers inhibition of AMPA/kainate receptors

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DJ-1 is not a deglycase and makes a modest contribution to cellular defense against methylglyoxal damage in neurons

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Management of post-transplant diabetes can be challenging, as immunosuppressive drugs such as glucocorticoids, calcineurin inhibitors, and mTOR (mammalian target of rapamycin) inhibitors are associated with induction of hyperglycemia or worsening of glucose control