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GSSG prevented TNF-induced activation of IKK-, an upstream kinase in the NF-B signaling pathway, by inducing IKK- glutathionylation (IKK--SSG formation)

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Our results supplement previous observations of high GPX levels in other tissues than brain, showing that heart, lung and muscle tissue of ringed seals ( Phoca hispida ) has elevated GPX activity compared to domestic pig tissues ( Sus scrofa domesticus ) (Vzquez-Medina et al., 2006)

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