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Furthermore, inhaled vaccine codisplaying wildtype RBD and Omicron variant RBD significantly prevents Omicron transmission in hamsters

These mechanisms are observed under controlled in vitro and in vivo experimental conditions where the peptide interacts with cellular and tissue systems

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Nevertheless, longer-term exposures are frequently studied, often in combination with multiple time points, to examine the time-course variation of the metabolome, to understand the sequence of molecular initiating events leading to an adverse outcome pathway, and chronic toxicity upon repeated exposure to a given compound (Silva et al., 2013