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Ultrathin sections (50 nm) were post-stained with Reynolds lead citrate and imaged in a Talos 120 transmission electron microscope at 120 kV acceleration voltage equipped with a bottom-mounted Ceta camera using the Maps software (Thermo Fisher Scientific, Eindhoven, The Netherlands)

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All data was analyzed using R software version 2.15 and Prism (Graphpad Software)

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