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The overexpression of perilipin 2 (PLIN2, also known as adipophilin), one of the most abundantly expressed LD proteins, protects LD from autophagy-dependent degradation, while its deficiency stimulates TG catabolism through autophagy, protecting mice against fatty liver diseases (Tsai et al., 2017)
[DOI] [PubMed] [Google Scholar] 113.Healy Z.R., Liu H., Holtzclaw W.D., Talalay P
Light-dependent sequestration of TIMELESS by CRYPTOCHROME
Early studies indicated that the peptide might stimulate lipolysis (fat breakdown) and inhibit lipogenesis (fat formation) in preclinical settings
H., Daugherty D
Inhibition of NMDA receptor expressed on islet cells can inactivate K ATP channels and ultimately improve blood glucose levels in type 2 diabetic mouse models [185]
