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Description
This is consistent with the methyl folate trap hypothesis (54), which predicts that, in vitamin B-12 deficiency, the inhibition of DNA synthesis and cell proliferation is removed upon administration of high doses of folic acid because of increased availability of nonmethylated folate

Ragan, M.A., McInerney, J.O

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If you're genuinely B12-deficient, correcting it can dramatically improve fatigue, brain fog, and exercise tolerance

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