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To achieve this, the guideline incorporates a systematic review to evaluate the overall body of evidence and provide recommendations that balance intended benefits and potential harms from the perspective of patient health

In one study related to AD, Omega-3 FA supplementation influenced the transition from gut microbiota balance to a symbiotic state, but the results were not significant enough ( Bifidobacteria and Lactobacilli ), thereby affecting the distribution of gut microbiota, and dietary addition of omega-3 polyunsaturated fatty acids increases the abundance and percentage of bifidobacteria in the gut of male Sprague-Dawley rats ( bifidobacteria ( Faecalibacterium and Veronella was detected in the IBD group, while the abundance of Bacteroides and Flavobacterium was decreased ( E