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PMID: 188 BonzanoSDallortoEBovettiSStuderMDe MarchisS

Depending on the cellular redox milieu and cell type, Fos and Jun can dimerize or interact with other transcription factors such as ATF, C/EBP and Maf leading to activation or inhibition of gene transcription of antioxidant and immunoactive proteins (169, 360)

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Additionally, we uncovered that inhibition of antiferroptosis mechanisms enhanced the anti-leukemic activity of APR-246 both in vitro and in vivo

Acute floaters: a sudden occurrence of floaters, sometimes associated with flashing lights, may indicate that a posterior vitreous detachment (P.V.D), retinal detachment, or other ocular emergency is occurring