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161, 166, 167 Alkalinization increases urothelial penetration of lidocaine and therefore is expected to improve efficacy, but it also can increase systemic absorption and potential toxicity

MBio 9(2):e02120-e2217 Carloni S, Bertocchi A, Mancinelli S, Bellini M, Erreni M, Borreca A et al (2021) Identification of a choroid plexus vascular barrier closing during intestinal inflammation