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Peak area integration and metabolite identification were performed using accurate mass and RT curated with in-house standard library compounds

doi: 10.1155/2017/1594074 30 CopmansD.KildgaardS.RasmussenS

Dysregulated iron homeostasis has been linked to hyperphosphorylation and NFT development (42)

Previous work from Wilsons laboratory has shown that the constant subcutaneous infusion of IGF-1 to monkeys with normal pituitary glands results in a sustained elevation in circulating concentrations of IGFBP-3
Effects of a novel pharmacologic inhibitor of myeloperoxidase in a mouse atherosclerosis model

Iron overload in cells impairs autophagy flux and ferroptosis by inhibiting activating transcription factor 4 (ATF4), while insufficient cellular iron initiates endoplasmic reticulum (ER) stress and leads to apoptosis
