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TRMs, such as alveolar macrophages and Kupffer cells, possess distinct ontogeny and metabolic baselines dictated by their organ-specific niches, whereas MDMs exhibit rapid, high-flux metabolic reprogramming upon recruitment to the infection site

DNA methylation is a fundamental signature of gene repression and has been used for the development of accurate age prediction tools, the so-called epigenetic clocks [121,122,123]

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In brief, animals were decapitated under deep anesthesia at the final phase of the experiment

[DOI] [PubMed] [Google Scholar] Oke O.E., Akosile O.A., Uyanga V.A., Oke F.O., Oni A.I., Tona K., Onagbesan O.M

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