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For BPC-157, the agency cited the potential for immunogenicity, peptide-related impurities, problems characterizing the active ingredient, and a lack of safety data for the proposed routes of administration

On the other hand, as confirmed by the binding free energy predictions showed that the positive control peptide

The basic workflow is: Define DOE in external DOE Software Copy design table into parameter sweep table in M-Star CFD GUI Run M-Star CFD simulations using Queue Collect results using Aggregator Copy data from Aggregator into Stat Ease Continue DOE analysis Model Description Agitated vessel with bottom mounted impeller 200 L tank Free surface model ON Scalar injected at t=30s Scalar relative standard deviation (RSD) computed Simulation stops when scalar RSD is below 5