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Intracellular toxic AGEs (TAGE) triggers numerous types of cell damage
doi: 10.1016/j.canlet.2024.217422 212 LiuWLiLBaiXZhangMLvWMaYet al

Danish, R., Lee, P., Mazur, T., Amrhein, J
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doi: 10.1038/s41467-023-42480-3 96 VegliaFTyurinVAMohammadyaniDBlasiMDuperretEKDonthireddyLet al

This facilitates cellular uptake and accumulation in organelles like mitochondria, where its positive charge drives electrostatic localization in the mitochondrial matrix (Nedu et al