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A novel two-nucleotide deletion in the ornithine transcarbamylase gene causing fatal hyperammonia in early pregnancy

The pathophysiology of neuropathic pain varies and includes ectopic activity in damaged nerves or in adjacent nerves, dorsal root ganglion (DRG) or central pathways, and peripheral and central sensitisation involving numerous molecular mechanisms

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Gandola M, Argenziano G, Barba C, Bassi R, Binazzi M, Landi G,

Such damage triggers the release of pro-inflammatory mediators, subsequently activating antigen-presenting cells (APCs) and fostering the maturation of CD4 + T cells