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Although these studies do not specifically differentiate between neuronal and astrocytic contributions, it is possible that the modulation of astrocytic A 1 and A 2A receptors may have an impact on the onset and progression of ALS, given the well-established importance of astrocytes in the disease [435]

Clinical trials for PD have had limited success to date, and there are still no effective neuroprotective therapies to suppress or slow down the progression of PD

This suggests that GHK-Cu and related peptides could be investigated as potential non-addictive research alternatives in the context of pain management, alongside opiate medications and NSAIDs, which are known for their potential side effects, including negative impacts on cardiovascular health

The trial is registered with the University Hospital Medical Information Network (UMIN) Clinical Trials Registry (UMIN000011118)

Use of growth factors for the treatment of Parkinson's disease

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