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In 2004, it was reported that subcutaneous (s.c.) administration of the BPC 157 peptide to rats (10 g/kg/day for 7 days) resulted in brain region-specific increases in serotonin synthesis [99], as determined by the precise alpha-[14C]methyl-L-tryptophan (alpha-MTrp) autoradiographic method

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It is thought that over time, the disease shifts from an early hypermetabolic state to a hypometabolic state with decreased metabolites (251) and reduced energy production (59), correlating with patient clinical profiles (185)

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Jing Li: Nothing to disclose
