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PMID: 37036576 J Clin MedAnlotinib Suppressed Ovarian Cancer Progression via Inducing G2/M Phase Arrest and Apoptosis

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This structural destabilization activates the CREB3ARF4mediated Golgi stress response, which upregulates pro-inflammatory and pro-apoptotic genes including CHOP, thereby exacerbating cellular injury

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For example, DNA methyltransferase inhibitors (DNMTis) and histone deacetylase inhibitors (HDACis) can be used to treat cancers because they change the patterns of DNA methylation and histone modification