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Deletion of npc1 specifically in PNs causes PN loss in WT mice (72), whereas the expression of npc1 specifically in PNs corrects cholesterol accumulation and prevents PN loss in npc1/ mice (73)

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It also ensures that supplementation remains within safe limits, reducing the risk of adverse effects

The coating materials rapid erosion over time is a disadvantage of the coating method

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Additionally, it is evident that a large percentage of the population is infected but also vaccinated against COVID-19, and even such scenarios could be the etiology of possible misdiagnoses [1,2,3,4,5]