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For tumor cells deficient in methythioadenosine phosphorylase (MTAP), Met depletion and inhibition of the key enzyme MAT2A in the Met metabolism pathway are possible therapeutic strategies

There is an urgent need to pinpoint patient-level risk factors and characteristics in order to successfully identify patients at a high risk of developing LC and to properly diagnose this syndrome

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Nevertheless, with the tension of ex- aminations came the relief that fol- lowed their completion

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