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Although they are not typically considered part of the BBB, microglia survey the CNS for microbes and have the capabilities to engulf and destroy those they encounter

Ingredients AQUA, GLYCERIN, TREHALOSE, 1,2-HEXANEDIOL, HYDROXYACETOPHENONE, SODIUM POLYGLUTAMATE, COPPER TRIPEPTIDE-1, AMMONIUM ACRYLOYLDIMETH YLTAURATE/VPPolycopolymer, Sodium HYALURONATE, PEONY albiflora ROOT EXTRACT, PENTYLENE GLYCOL, DIPEPTIDE GUARANTEED BUTYROYL Benzylamide DIACETATE, PIPER Methysticum ROOT EXTRACT, PHASEOLUS RADIUS seed EXTRACT, DISODIUM EDTA, t-BUTYL ALCOHOL Directions Apply a few drops to the face in the morning and evening

We also include post-mortem ex-vivo OCT data, co-registered to the histology in Figure 3B to demonstrate features such as the small 2060 M drusen seen in histology are difficult to assess in post mortem OCT and that the other changes being shown indicative of pathologies in retinas might be invisible to current commonly available clinical assessments

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10.1523/JNEUROSCI.4542-05.2006 J

Future strategies should incorporate personalized microbiome profiling, enabling tailored interventions that target individual microbial deficiencies, optimize immune modulation, and maximize therapeutic efficacy (Porcari et al., 2023)