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Animo Acids: (Sodium L-Pyrrolidone Carboxylate, Sodium Lactate, LArginine, L-Aspartic Acid, L-Pyrrolidonecarboxylic Acid, Glycine, L-Alanine, L-Serine, L-Valine, L-Proline, L-threonine, L-Isoleucine, L-Histidine, L-Phenylalanine)

However, it has been described that these substrates are produced in the cytosol to induce Ca 2+ release mainly from the endoplasmic reticulum or the extracellular space by activating Ca 2+ channels

Ion pumps actively transporting ions such as H + , Na + , K + , Ca 2+ and Cu 2+ produce and maintain electrochemical ion gradients across the cellular membranes which are subsequently used by secondary active ion-coupled transporters to deliver molecules in antiport (also known as exchange) or symport (also known as co-transport) of these ions (45, 46)

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